All Compounds
12 compounds cataloged with risk profiles and natural alternatives
Browse by Outcome, Not Just Compound Name
Most visitors are really looking for stamina, focus, muscle growth, recovery, or appetite control. Start from those routes and compare compounds in context.
Popular Goal Hubs
Browse Compounds by Goal
Cognitive Enhancement
Cognition & Longevity
Improving focus, memory, learning, and mental clarity.
Improve attention, memory, and mental stamina with lower-risk options.
Muscle Growth
Performance
Building lean muscle mass through training and nutrition optimization.
Build lean mass with evidence-backed training, protein, and recovery basics.
Sleep Quality
Recovery & Wellness
Improving sleep onset, duration, and quality of deep sleep.
Improve deep sleep, recovery quality, and next-day performance.
AC-262
High RiskPartial androgen receptor agonist with ~66% of testosterone anabolic activity but ~27% androgenic activity.
GW-501516
High RiskNot a SARM β PPARΞ΄ agonist that enhances fat oxidation and endurance. Abandoned by GSK.
LGD-3303
High RiskNon-steroidal SARM developed by Ligand Pharmaceuticals. Supposedly more selective than LGD-4033.
LGD-4033
High RiskNon-steroidal SARM that binds androgen receptors with high affinity. Developed for muscle wasting.
MK-2866
High RiskOne of the most studied SARMs. Selective AR modulator developed for muscle wasting and osteoporosis.
MK-677
High RiskNot actually a SARM β it is an oral growth hormone secretagogue that mimics ghrelin. Increases GH and IGF-1.
RAD-140
High RiskSelective androgen receptor modulator that binds AR in muscle and bone with claimed tissue selectivity.
RAD-150
High RiskEsterified version of RAD-140 with claimed longer half-life and improved bioavailability.
S-23
High RiskPotent SARM with strong androgen receptor binding. One of the most suppressive SARMs.
S-4
High RiskSARM with moderate binding affinity. Known for distinctive vision side effect (yellow tint).
SR-9009
Moderate RiskRev-ErbA agonist that affects circadian rhythm and metabolic processes. Not actually a SARM.
YK-11
High RiskPartial androgen receptor agonist that also acts as a myostatin inhibitor. Steroidal structure despite SARM classification.
About Our Compound Database
NaturalOverNeedles maintains one of the most comprehensive databases of peptides, SARMs, GLP-1 receptor agonists, nootropics, and research chemicals available online. Each compound is cataloged with detailed risk profiles, mechanism of action, typical dosages, FDA status, and most importantly β evidence-graded natural alternatives.
Our mission is to help you make informed decisions about your health by providing transparent, research-backed information about both synthetic compounds and their natural counterparts.