All Compounds
38 compounds cataloged with risk profiles and natural alternatives
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Browse Compounds by Goal
Cognitive Enhancement
Cognition & Longevity
Improving focus, memory, learning, and mental clarity.
Improve attention, memory, and mental stamina with lower-risk options.
Muscle Growth
Performance
Building lean muscle mass through training and nutrition optimization.
Build lean mass with evidence-backed training, protein, and recovery basics.
Sleep Quality
Recovery & Wellness
Improving sleep onset, duration, and quality of deep sleep.
Improve deep sleep, recovery quality, and next-day performance.
5-Amino-1MQ
High RiskNNMT inhibitor that increases NAD+ and SAM levels. Claimed to increase cellular energy expenditure and fat metabolism.
AOD-9604
Moderate RiskModified fragment of human growth hormone (HGH 176-191) that stimulates lipolysis without affecting blood sugar or growth.
BPC-157
High RiskGastric pentadecapeptide that promotes angiogenesis, modulates nitric oxide system, and interacts with dopamine and serotonin systems. Studied for wound healing and tissue repair in animal models.
BPC-157 Arginate
High RiskArginine salt form of BPC-157, claimed to be more stable for oral administration.
Cerebrolysin
Moderate RiskPorcine brain-derived peptide mixture with neurotrophic effects. Used in Europe/Asia for stroke and dementia.
CJC-1295
High RiskGrowth hormone releasing hormone (GHRH) analog that stimulates growth hormone secretion from the pituitary gland.
Dihexa
High RiskAngiotensin IV analog claimed to be 7 orders of magnitude more potent than BDNF at promoting synaptic connectivity.
DSIP
Moderate RiskNeuropeptide that modulates sleep architecture, particularly delta wave sleep. May interact with GABA and serotonin systems.
Epithalon
High RiskSynthetic tetrapeptide that stimulates telomerase production to lengthen telomeres. Anti-aging claims.
Follistatin-344
High RiskBinds and neutralizes myostatin and activin, theoretically allowing enhanced muscle growth beyond natural limits.
Fragment 176-191
Moderate RiskTruncated form of HGH comprising amino acids 176-191. Claims to stimulate fat burning without other GH effects.
FTPP (Adipotide)
High RiskTargets and destroys blood vessels feeding white adipose tissue, causing fat cell death.
GHK
Low RiskTripeptide found naturally in plasma. Promotes wound healing, collagen synthesis, and gene expression modulation.
GHK-Cu
Low RiskNaturally occurring copper-binding peptide involved in wound healing, collagen synthesis, and anti-inflammatory signaling.
GHRP-2
High RiskGH secretagogue similar to GHRP-6 but with less appetite stimulation. Activates ghrelin receptor.
GHRP-6
High RiskGhrelin mimetic that stimulates growth hormone release and increases appetite through GHS-R1a receptor activation.
Hexarelin
High RiskPotent growth hormone secretagogue. Strongest GH release of any GHRP but causes rapid desensitization.
Humanin
Moderate RiskMitochondrial-derived peptide with cytoprotective, anti-inflammatory, and anti-apoptotic properties.
IGF-1 LR3
High RiskModified insulin-like growth factor with extended half-life. Promotes cell growth, differentiation, and survival.
Ipamorelin
Moderate RiskSelective growth hormone secretagogue that mimics ghrelin to stimulate GH release. More selective than other GHRPs.
Kisspeptin
High RiskNeuropeptide that stimulates GnRH release, which triggers LH and FSH production. Key regulator of reproductive hormones.
KPV
Moderate RiskC-terminal tripeptide of alpha-MSH with anti-inflammatory properties. Studied for gut inflammation and IBD.
LL-37
High RiskAntimicrobial peptide naturally produced by the immune system. Kills bacteria, viruses, and fungi.
Melanotan II
High RiskNon-selective melanocortin agonist that stimulates melanin production (tanning), libido, and appetite suppression.
About Our Compound Database
NaturalOverNeedles maintains one of the most comprehensive databases of peptides, SARMs, GLP-1 receptor agonists, nootropics, and research chemicals available online. Each compound is cataloged with detailed risk profiles, mechanism of action, typical dosages, FDA status, and most importantly โ evidence-graded natural alternatives.
Our mission is to help you make informed decisions about your health by providing transparent, research-backed information about both synthetic compounds and their natural counterparts.